A Canadian study suggests that combination treatment with RESTYLANE and Botox® is more effective than either product on its own for correcting glabellar lines (lines between the eyebrows). The study comprised 38 women with moderate to severe glabellar lines who were randomised to receive RESTYLANE alone or Botox® plus RESTYLANE.

The combination of RESTYLANE and Botox® proved significantly more effective than RESTYLANE alone over a 28-week follow-up period. The study also revealed that injection-related pain was rated as lower when RESTYLANE was injected after Botox®, suggesting that Botox® has some analgesic effect. (Carruthers, A. New evidence of hyaluronic acid (NASHA) as a dermal filler. 11th congress of the EADV, Prague, Czech Republic; 4 Oct 2002)

RESTYLANE is a trademark owned by Q-MED AB. BOTOX® is a registered trademark of Allergan Inc.

See also Botox®, Restylane, Dermal Fillers